Expertise
Notre savoir-faire en libération ciblée et multicouches
At Naturacare, we master bi-layer and tri-layer technologies to design controlled-release tablets that optimise kinetics, bioavaibility, and active ingredients stability.
3
multilayer tablet lines
Release
immediate or prolonged
Formats
multiple formats available
Our expertise
Developing a multilayer controlled-release tablet is both a technical and strategic process
Mastery of bi-layer and tri-layer technologies
Our bi-layer and tri-layer compression technologies provide precise control over release profiles and enable the separation of actives that may interact.
Each layer serves a specific function (immediate, sustained, or sequential release) ensuring continuous diffusion of actives and optimised bioavailability.
This technological expertise helps improve digestive tolerance, reduce the number of daily intakes, and support better consumer adherence.
Our production sites in France and Italy (Milan) integrate high-precision multilayer compression lines, ensuring consistent reproducibility from R&D development to industrial production.

Analytical control and validation of release profiles
Each development includes rigorous analytical control to guarantee performance and consistency.
Our teams conduct dissolution tests and release profile studies to confirm the kinetics and ensure compliance with specifications.

From technology to product experience
Controlled-release and multilayer technologies are also powerful storytelling and differentiation levers. Visible or coloured layers can illustrate a dual action (immediate/prolonged, day/night, body/mind), visually reinforcing the value proposition. These technologies support a wide range of health categories, including sleep, energy, stress, immunity, and vitality.
Examples:
- Immediate & prolonged action: a flash-effect active ingredient combined with sequential diffusion over 6 to 24 hours
- “Body & Mind” concept: two complementary actions within the same tablet

Want to know more about our multilayer & controlled-release expertise?
NaturaGo®: a private label offer of controlled-release multilayer products
With NaturaGo®, accelerate your launches with a selection of ready-to-market multilayer controlled-release formulas. Innovative, high-performance, and sensory-driven supplements designed to optimise active bioavailability and deliver long-lasting effectiveness throughout the day or night.
Frequently asked questions about controlled release & multilayer tablets
What are the advantages of controlled release?
Controlled release ensures regulated diffusion of actives, improved bioavailability, and reduced number of daily intakes — enhancing comfort and compliance.
Can incompatible ingredients be combined in a multilayer tablet?
Yes. Multilayer technology allows the separation of sensitive or incompatible actives, ensuring their stability and effectiveness over time.
How can multilayer technology reinforce product storytelling?
Visible or coloured layers can illustrate dual action (day/night, immediate/prolonged), visually reinforcing the concept on the packaging and enhancing consumer appeal.
Our other areas of expertise






