Expertise

Notre savoir-faire en libération ciblée et multicouches

At Naturacare, we master bi-layer and tri-layer technologies to design controlled-release tablets that optimise kinetics, bioavaibility, and active ingredients stability.

3

multilayer tablet lines

Release

immediate or prolonged

Formats

multiple formats available

Our expertise

Developing a multilayer controlled-release tablet is both a technical and strategic process

  • R
    Mastery of bi-layer and tri-layer compression to modulate release and ensure formula stability
  • R
    In-depth formulation expertise to select functional excipients and matrices that deliver controlled and prolonged release
  • R
    Rigorous analytical control, including dissolution testing, to validate release profiles and performance

Mastery of bi-layer and tri-layer technologies

Our bi-layer and tri-layer compression technologies provide precise control over release profiles and enable the separation of actives that may interact.
Each layer serves a specific function (immediate, sustained, or sequential release) ensuring continuous diffusion of actives and optimised bioavailability.

This technological expertise helps improve digestive tolerance, reduce the number of daily intakes, and support better consumer adherence.

Our production sites in France and Italy (Milan) integrate high-precision multilayer compression lines, ensuring consistent reproducibility from R&D development to industrial production.

Analytical control and validation of release profiles

Each development includes rigorous analytical control to guarantee performance and consistency.
Our teams conduct dissolution tests and release profile studies to confirm the kinetics and ensure compliance with specifications.

From technology to product experience

Controlled-release and multilayer technologies are also powerful storytelling and differentiation levers. Visible or coloured layers can illustrate a dual action (immediate/prolonged, day/night, body/mind), visually reinforcing the value proposition. These technologies support a wide range of health categories, including sleep, energy, stress, immunity, and vitality.

Examples:

  • Immediate & prolonged action: a flash-effect active ingredient combined with sequential diffusion over 6 to 24 hours
  • “Body & Mind” concept: two complementary actions within the same tablet

Want to know more about our multilayer & controlled-release expertise?

NaturaGo®: a private label offer of controlled-release multilayer products

With NaturaGo®, accelerate your launches with a selection of ready-to-market multilayer controlled-release formulas. Innovative, high-performance, and sensory-driven supplements designed to optimise active bioavailability and deliver long-lasting effectiveness throughout the day or night.

Vital Extend

Bi-layer 2-in-1 tablet offering immediate energising effect and prolonged action for up to 8 hours, providing continuous energy throughout the day.

Night Care Extend

Bi-layer dual-action tablet combining melatonin, magnesium, B6, and B12 for sleep initiation, while the prolonged-release layer with poppy and lemon balm extracts maintains sleep quality throughout the night.

Trio Iron Extend

Tri-layer tablet containing three forms of iron, released sequentially for optimal absorption.

Frequently asked questions about controlled release & multilayer tablets

What are the advantages of controlled release?

Controlled release ensures regulated diffusion of actives, improved bioavailability, and reduced number of daily intakes — enhancing comfort and compliance.

Can incompatible ingredients be combined in a multilayer tablet?

Yes. Multilayer technology allows the separation of sensitive or incompatible actives, ensuring their stability and effectiveness over time.

How can multilayer technology reinforce product storytelling?

Visible or coloured layers can illustrate dual action (day/night, immediate/prolonged), visually reinforcing the concept on the packaging and enhancing consumer appeal.

Our other areas of expertise